NMDA receptor encephalitis

Orpha code: 217253OMIM code:

Definition

A rare limbic encephalitis characterized by the presence of autoantibodies against NMDA receptors in serum and cerebrospinal fluid. It may be of paraneoplastic (most commonly associated with ovarian teratoma) or non-paraneoplastic origin and is life-threatening but potentially treatable. Patients present with acute behavioral change, psychosis, and catatonia, rapidly progressing to seizures, memory deficit, dyskinesias, speech problems, and autonomic and breathing dysregulation.

Disease data
Classification

Disease

Synonyms
Limbic encephalitis with N-methyl-D-aspartate receptor antibodies
Zapalenie układu limbicznego z przeciwciałami przeciwko receptorom N-metylo-D-asparaginowym
Zapalenie mózgu związane z receptorem NMDA
Limbic encephalitis with NMDA receptor antibodies
N-methyl-D-aspartate receptor encephalitis
NMDARE
anti-NMDA receptor encephalitis
ORPHA code
217253
OMIM code
-
ICD10 code
G13.1
ICD11 code
-

No additional description.

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