Median cleft lip/mandible

Orpha code: 2006OMIM code:

Definition

A rare median facial cleft characterized by median cleft of the lower lip (ranging in extent from a notch in the vermilion to a complete cleft involving the tongue, lower lip, and chin, and extending to the cervical region), median cleft of the mandible (ranging from notching to a complete cleft), and anomaly of the tongue including bifid tongue and tongue tie. Associated features in severe cases may include absent hyoid, thyroid cartilage, and manubrium sterni, as well as atrophic neck muscles.

Disease data
Classification

Morphological anomaly

Synonyms
Median cleft lower facial stage
Pośrodkowy rozszczep dolnej części twarzy
ORPHA code
2006
OMIM code
-
ICD10 code
Q36.1
ICD11 code
-

No additional description.

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