Diethylstilbestrol syndrome

Orpha code: 1916OMIM code:

Definicja

A malformation syndrome reported in offspring (children and grandchildren) of women exposed to diethylstilbestrol (DES) during pregnancy and is characterized by reproductive tract malformations, decreased fertility and increased risk of developing clear cell carcinoma of the vagina and cervix in young women. Reproductive malformations reported in DES syndrome include small, T-shaped uteri and other uterotubal anomalies that increase the risk of miscarriages in women and epididymal cysts, microphallus, cryptorchidism, or testicular hypoplasia in men. DES, a synthetic nonsteroidal estrogen was widely prescribed from 1940-1970 to prevent miscarriage.

Disease data
Klasyfikacja

Malformation syndrome

Synonimy
DES embryofetopathy
Embriofetopatia dietylstilbestrolowa
Embriofetopatia DES
Zespół DES
DES syndrome
Diethylstilbestrol embryofetopathy
Distilbene embryofetopathy
Kod ORPHA
1916
Kod OMIM
-
Kod ICD10
Q86.8
Kod ICD11
LB44.6

No additional description.

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