Male infertility due to globozoospermia

Orpha code: 171709OMIM code: 613958

Definition

Male infertility due to globozoospermia is a male infertility due to sperm disorder characterized by the presence, in sperm, of a large majority of round-headed spermatozoa that lack the acrosome and have an aberrant nuclear membrane and midpiece defects. The acrosomeless spermatozoa is not able to penetrate the zona pellucida and thus fertilization failures, even with intracytoplasmic sperm injection, are frequent.

Disease data
Classification

Clinical subtype

Synonyms
Male infertility due to round-headed spermatozoa
Niepłodność męska z powodu spermatozoa z okrągłą główką
Round-headed sperm syndrome
ORPHA code
171709
OMIM code
613958
ICD10 code
N46
ICD11 code
-

No additional description.

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