Craniotelencephalic dysplasia

Orpha code: 1528OMIM code: 218670

Definition

Craniotelencephalic dysplasia is an extremely rare, genetic developmental defect during embryogenesis syndrome characterized by craniosynostosis with frontal encephalocele and various additional brain anomalies (severe hydrocephalus, agenesis of the corpus callosum, lissencephaly and polymicrogyria, parenchymal cysts, septo-optic dysplasia) resulting in marked cerebral dysfunction, seizures and very severe psychomotor delay. There have been no further descriptions in the literature since 1983.

Disease data
Classification

Malformation syndrome

ORPHA code
1528
OMIM code
218670
ICD10 code
Q04.3
ICD11 code
LD20.1

No additional description.

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