Microphthalmia with brain and digit anomalies

Orpha code: 139471OMIM code: 607932

Definition

Microphthalmia with brain and digit anomalies is characterised by anophthalmia or microphthalmia, retinal dystrophy, and/or myopia, associated in some cases with cerebral anomalies. It has been described in two families. Polydactyly may also be present. Linkage analysis allowed identification of mutations in the <I> BMP4</I> gene, which has already been shown to play a role in eye development.

Disease data
Classification

Malformation syndrome

Synonyms
Bakrania-Ragge syndrome
MCOPS6
Mikroftalmia syndromiczna typu 6
Zespół Bakrania i Ragge
MCOPS6
Syndromic microphthalmia type 6
ORPHA code
139471
OMIM code
607932
ICD10 code
Q11.2
ICD11 code
-

No additional description.

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