Male infertility due to large-headed multiflagellar polyploid spermatozoa

Orpha code: 137893OMIM code: 243060

Definition

A rare male infertility due to a sperm disorder characterized by the presence, in sperm, of a very high percentage of spermatozoa with enlarged head, irregular head shape, multiple flagella, and abnormal midpiece and acrosome. It is generally associated with severe oligoasthenozoospermia and a high rate of sperm chromosomal abnormalities (polyploidy, aneuploidy).

Disease data
Classification

Clinical subtype

Synonyms
Macrocephalic sperm head syndrome
Male infertility due to macrozoospermia
ORPHA code
137893
OMIM code
243060
ICD10 code
N46
ICD11 code
MF7Y

No additional description.

Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl