Ostra białaczka szpikowa z dysplazją wieloliniową

Kod Orpha: 86845Kod OMIM: 601626

Definicja

A rare acute myeloid leukemia (AML) characterized by the presence of acute leukemia with at least 20% peripheral blood or bone marrow blasts with morphological features of myelodysplasia, or occurrence in patients with a prior history of a myelodysplastic syndrome (MDS) or myelodysplastic/myeloproliferative neoplasm, with MDS-related cytogenetic abnormalities, in the absence of specific genetic abnormalities characteristic of AML with recurrent genetic abnormalities. Prior cytotoxic or radiation therapy for an unrelated disease must be excluded. The condition occurs mainly in elderly patients and is rare in children. Patients often present with severe pancytopenia. Prognosis is generally poor.

Dane
Klasyfikacja

Choroba

Synonimy
AML with multilineage dysplasia
AML z dysplazją wieloliniową
AML with myelodysplasia-related features
Acute myeloid leukemia with multilineage dysplasia
Kod ORPHA
86845
Kod OMIM
601626
Kod ICD10
C92.8
Kod ICD11
2A60.1

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