Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition A rare skin tumor characterized by an asymptomatic, solitary, often ulcerated nodule most commonly located in the face, involving the deep dermis, subcutaneous tissue, and skeletal muscle and fascia. Histopathologically, the lesion is composed of aggregates of atypical basaloid cells with numerous mitoses. Typical features include shadow cells, keratin cysts, and trichohyalin and keratohyalin granules. The tumor is locally aggressive and shows a tendency to recur after incomplete excision. Regional lymph node or visceral metastasis has been reported. Disease data Classification Disease Synonyms Calcified epithelial carcinoma of Malherbe Nabłoniak wapniejący złośliwy Nabłoniakorak wapniejący Rak nabłonkowy wapniejący Malherbego Calcifying epitheliocarcinoma Malignant pilomatricoma Trichomatrical carcinoma ORPHA code 499182 OMIM code - ICD10 code C44.4 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl