Pilomatrix carcinoma

Orpha code: 499182OMIM code:

Definition

A rare skin tumor characterized by an asymptomatic, solitary, often ulcerated nodule most commonly located in the face, involving the deep dermis, subcutaneous tissue, and skeletal muscle and fascia. Histopathologically, the lesion is composed of aggregates of atypical basaloid cells with numerous mitoses. Typical features include shadow cells, keratin cysts, and trichohyalin and keratohyalin granules. The tumor is locally aggressive and shows a tendency to recur after incomplete excision. Regional lymph node or visceral metastasis has been reported.

Disease data
Classification

Disease

Synonyms
Calcified epithelial carcinoma of Malherbe
Nabłoniak wapniejący złośliwy
Nabłoniakorak wapniejący
Rak nabłonkowy wapniejący Malherbego
Calcifying epitheliocarcinoma
Malignant pilomatricoma
Trichomatrical carcinoma
ORPHA code
499182
OMIM code
-
ICD10 code
C44.4
ICD11 code
-

No additional description.

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