Sporadic fetal brain disruption sequence

Definition

Sporadic fetal brain disruption sequence is a rare, non-syndromic, central nervous system malformation disorder characterized by severe microcephaly (average occipitofrontal circumference -5.8 SD), overlapping sutures, keel-like occipital bone prominence, scalp rugae with normal hair pattern and signs of neurological impairment. Brain imaging may show ventriculomegaly, cortical tissue deficit, and hydranencephaly.

Disease data

Classification

Malformation syndrome

ORPHA code

1665

OMIM code

ICD10 code

Q02

ICD11 code

*Soruce