Yolk sac tumor

Orpha code: 876OMIM code: 273300

Definition

A rare germ cell tumor characterized by multiple patterns reflecting endodermal extraembryonal differentiation (secondary yolk sac and allantois) or endodermal somatic tissues (intestine, liver, and mesenchyme). The tumors most commonly occur in the second or third decade of life. They are typically located in the gonads, occasionally also in other regions. Patients present with a pelvic mass and/or abdominal pain (females) or an often painless, unilateral testicular mass (males). Elevated serum alpha fetoprotein is a common laboratory finding.

Disease data
Classification

Disease

Synonyms
Endodermal sinus tumor
guz pęcherzyka żółtkowego
ORPHA code
876
OMIM code
273300
ICD10 code
C62.9
ICD11 code
2F34

No additional description.

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