Acute promyelocytic leukemia

Orpha code: 520OMIM code: 612376

Definition

An aggressive form of acute myeloid leukemia (AML), characterized by arrest of leukocyte differentiation at the promyelocyte stage, due to a specific chromosomal translocation t(15;17) in myeloid cells, and manifests with easy bruising, hemorrhagic diathesis and fatigue.

Disease data
Classification

Disease

Synonyms
AML M3
APML
AML M3
Ostra białaczka mieloblastyczna 3
AML z t(15;17)(q22;q12);(PML/RARalpha) i wariantami
Ostra białaczka mielocytarna z t(15;17)(q22;q12);(PML/RARalpha) i wariantami
AML with t(15;17)(q22;q12);(PML/RARalpha) and variants
APML
Acute myeloblastic leukemia 3
Acute myeloid leukemia with t(15;17)(q22;q12);(PML/RARalpha) and variants
ORPHA code
520
OMIM code
612376
ICD10 code
C92.4
ICD11 code
XH1A50

No additional description.

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