Medium chain acyl-CoA dehydrogenase deficiency

Orpha code: 42OMIM code: 201450

Definition

Medium chain acyl-CoA dehydrogenase (MCAD) deficiency (MCADD) is an inborn error of mitochondrial fatty acid oxidation characterized by a rapidly progressive metabolic crisis, often presenting as hypoketotic hypoglycemia, lethargy, vomiting, seizures and coma, which can be fatal in the absence of emergency medical intervention.

Disease data
Classification

Disease

Synonyms
ACADM deficiency
MCADD
Niedobór MCAD
Niedobór ACADM
Niedobór dehydrogenazy średnich łańcuchów acetylo-koenzymu A
Niedobór karnityny wtórny do niedoboru dehydrogenazy średnich łańcuchów acetylo-CoA
Carnitine deficiency secondary to medium-chain acyl-CoA dehydrogenase deficiency
MCAD deficiency
MCADD
Medium chain acyl-coenzyme A dehydrogenase deficiency
ORPHA code
42
OMIM code
201450
ICD10 code
E71.3
ICD11 code
5C52.01

No additional description.

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