Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition Persistent polyclonal B-cell lymphocytosis (PPBL) is a rare, generally benign, lymphoproliferative hematological disease characterized by: chronic, stable, persistent, polyclonal lymphocytosis of memory B-cell origin, the presence of binucleated lymphocytes in the peripheral blood, and a polyclonal increase in serum immunoglobulin M (IgM). Patients are most frequently asymptomatic or may present with mild splenomegaly. Disease data Classification Disease Synonyms PPBL PPBL Przetrwała poliklonalna limfocytoza B-komórkowa z limfocytami z podwójnym jądrem Persistent polyclonal B-cell lymphocytosis with binucleated lymphocytes ORPHA code 300324 OMIM code 606445 ICD10 code D72.8 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl