Vitamin B12-unresponsive methylmalonic acidemia

Orpha code: 27OMIM code: 251000

Definition

Vitamin B12-unresponsive methylmalonic acidemia is an inborn error of vitamin B12 (cobalamin) metabolism characterized by recurrent ketoacidotic crises or transient vomiting, dehydration, hypotonia and intellectual deficit, which does not respond to administration of vitamin B12. There are two types of vitamin B12-unresponsive methylmalonic acidemia: <i>mut0</i> and <i>mut-</i> (see these terms).

Disease data
Classification

Disease

Synonyms
Methylmalonyl-CoA mutase deficiency
Acyduria metylomalonowa niereagująca na witaminę B12
Methylmalonyl-Coenzyme A mutase deficiency
Vitamin B12-unresponsive methylmalonic aciduria
ORPHA code
27
OMIM code
251000
ICD10 code
E71.1
ICD11 code
5C50.E0

No additional description.

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