Non-epidermolytic palmoplantar keratoderma

Orpha code: 2337OMIM code: 600231

Definition

A rare, isolated, diffuse palmoplantar keratoderma disorder characterized by diffuse, homogeneous, mild to thick, yellowish palmoplantar hyperkeratosis (sometimes spreading over the dorsal aspect of fingers), which presents a white spongy appearance following exposure to water, frequently associated with dermatophyte infections. Hyperhydrosis is usually present and skin biopsy shows non-epidermolytic changes.

Disease data
Classification

Disease

Synonyms
Autosomal dominant diffuse palmoplantar keratoderma, Norrbotten type
NEPPK
Rozlany rogowiec dłoniowo-podeszwowy, typ botnicki
Autosomalny dominujący rozlany rogowiec dłoni i stóp, typ Norrbotten
Diffuse palmoplantar keratoderma, Bothnian type
NEPPK
ORPHA code
2337
OMIM code
600231
ICD10 code
Q82.8
ICD11 code
EC20.30

No additional description.

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