Beta-ketothiolase deficiency

Orpha code: 134OMIM code: 203750

Definicja

A rare, genetic organic aciduria affecting ketone body metabolism and the catabolism of isoleucine and characterized by intermittent ketoacidotic episodes associated with vomiting, dyspnea, tachypnoea, hypotonia, lethargy and coma, with an onset during infancy and usually ceasing by adolescence.

Disease data
Klasyfikacja

Disease

Synonimy
3-ketothiolase deficiency
Kwasica alfa metyloacetooctowa
Niedobór 3-ketotiolazy
Niedobór 3-oksotiolazy
Niedobór mitochondrialnej tiolazy acetoacetylo-koenzymu A
Niedobór T2
Niedobór tiolazy alfa-metylo-acetoacetylo-CoA
3-oxothiolase deficiency
Alpha methylacetoacetic aciduria
Alpha-methyl-acetoacetyl-CoA thiolase deficiency
Mitochondrial acetoacetyl-coenzyme A thiolase deficiency
T2 deficiency
Kod ORPHA
134
Kod OMIM
203750
Kod ICD10
E71.1
Kod ICD11
5C50.DY

No additional description.

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